The problem with Nickel isn't the impurities it is the Nickel.
Google Nickel Toxicity and you will see in can be very hazardous if you consume enough of it. You will also find that some scientists believe it is required by the human body for life.
You be the judge.
It is my own personal belief that you will never consume enough nickel to harm yourself by vaping, torching or dry firing the stuff.
As far as cleanliness of the wire I believe Lighting Vapor suggest at the minimum you clean the wire with a solvent and then rinse and dry before use.
Correct, for all intents and purposes Ni200 is pure nickel.
The health concerns are: certain nickel compounds, and nickel metal particulates.
The most dangerous are nickel compounds like nickel carbonyl, nickel chloride, nickel sulfide, nickel acetate, etc.
The less dangerous are solid metal particulates and basic nickel oxide, which is what can form when nickel metal is heated past 700 degrees f (glowing coils).
The least dangerous is solid metal mass like nickel wire itself.
We have no evidence that nickel particulate enters the vapor stream. We have no evidence that nickel oxide enters the vapor stream.