I use TC with SS at anywhere between 370 F and 415 F. I add 8% water to my VG/Nicotine mix, no PG. The 8% water gives a viscosity approximately equal to 30% PG. I don't like PG and it does not like me.
That is definitely all pluses for safety.
In my previous post I forgot to also mention that just as the PG and VG can break down at higher temps, we do not know what happens to all the flavors at those temps. It may be nothing, it may be bad for some and not for others. That is an "unknown risk" at this point. I would still say it's safer than smoking though.