When I did the round 2 WTA extraction, I used 300 grams of tobacco and achieved a yield of 2.5 grams of tobacco alkaloids. Based on what I expected, this probably represents a 50 - 70% yield. There really aren't hard number available on various RYO tobaccos.
I took the purified alkaloids and mixed them up with PG/VG to produce ~80 mL of a 30 mg/mL WTA liquid.
Here is what 300 grams of tobacco looks like, this is the tobacco left over after the alkaloids were extracted, I simply dried it and put it in a container that everyone is familiar with to provide scale:
A two-liter plastic soda bottle nearly full with 300 grams (10.6 ounces) of extracted tobacco. (Thanks again to Exo for hosting).
If instead of extracting this tobacco, I rolled it up into cigarettes, it would produce around 300 cigarettes.
Now here's the fun part, I believe I got perhaps 70% the alkaloids out of the tobacco. This means that this tobacco originally contained about 3.6 grams of tobacco alkaloids. Due to the roughly 10% efficiency of cigarettes at delivering nicotine and the other tobacco alkaloids, smoking those 15 packs of cigarettes would deliver only 0.36 grams of alkaloids (and a hell of a lot of tar). Meanwhile, I recovered 2.5 grams of alkaloids, and at the ~40% efficiency of vaping, 1 gram of alkaloids would be delivered via vaping the 80 mL of 30 mg/mL WTA liquid.
That's right, vaping this bottle of tobacco, even at a fairly modest 70% alkaloid recovery is still ~2.8X more efficient at delivering the alkaloids (1 gram vs 0.36 gram) as smoking it.
At 2.5 mL/day WTA liquid consumption, the ~80 mL of 30 mg WTA liquid would last 32 days and deliver 30 mg of alkaloids per day (~27 mg nicotine, ~3 mg other alkaloids).
At 3.6 grams of alkaloids divided by 300 cigarettes, each cigarette would contain 12 mg of alkaloids. At 10% efficiency, each cigarette would deliver 1.2 mg of alkaloids. So to get the same daily alkaloid dose (30 mg) from cigarettes as from 2.5 mL of the WTA liquid, one would have to smoke 25 cigarettes per day. The 300 cigarettes would last 12 days compared to 32 days for the WTA liquid.
The implication of this mushrooms when we consider that we would need to smoke ~800 cigarettes to get the same alkaloid delivery as vaping 2.5 mL per day of the 30 mg/mL WTA liquid over a 32 day period.
Harm reduction anybody?
I took the purified alkaloids and mixed them up with PG/VG to produce ~80 mL of a 30 mg/mL WTA liquid.
Here is what 300 grams of tobacco looks like, this is the tobacco left over after the alkaloids were extracted, I simply dried it and put it in a container that everyone is familiar with to provide scale:

A two-liter plastic soda bottle nearly full with 300 grams (10.6 ounces) of extracted tobacco. (Thanks again to Exo for hosting).
If instead of extracting this tobacco, I rolled it up into cigarettes, it would produce around 300 cigarettes.
Now here's the fun part, I believe I got perhaps 70% the alkaloids out of the tobacco. This means that this tobacco originally contained about 3.6 grams of tobacco alkaloids. Due to the roughly 10% efficiency of cigarettes at delivering nicotine and the other tobacco alkaloids, smoking those 15 packs of cigarettes would deliver only 0.36 grams of alkaloids (and a hell of a lot of tar). Meanwhile, I recovered 2.5 grams of alkaloids, and at the ~40% efficiency of vaping, 1 gram of alkaloids would be delivered via vaping the 80 mL of 30 mg/mL WTA liquid.
That's right, vaping this bottle of tobacco, even at a fairly modest 70% alkaloid recovery is still ~2.8X more efficient at delivering the alkaloids (1 gram vs 0.36 gram) as smoking it.
At 2.5 mL/day WTA liquid consumption, the ~80 mL of 30 mg WTA liquid would last 32 days and deliver 30 mg of alkaloids per day (~27 mg nicotine, ~3 mg other alkaloids).
At 3.6 grams of alkaloids divided by 300 cigarettes, each cigarette would contain 12 mg of alkaloids. At 10% efficiency, each cigarette would deliver 1.2 mg of alkaloids. So to get the same daily alkaloid dose (30 mg) from cigarettes as from 2.5 mL of the WTA liquid, one would have to smoke 25 cigarettes per day. The 300 cigarettes would last 12 days compared to 32 days for the WTA liquid.
The implication of this mushrooms when we consider that we would need to smoke ~800 cigarettes to get the same alkaloid delivery as vaping 2.5 mL per day of the 30 mg/mL WTA liquid over a 32 day period.
Harm reduction anybody?
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