Curious - how well does the Darwin work with very high res atomizers? I mean in the 4.5 - 5.5 ohm range. Can it still pump 12+ watts through these? If so, is there any tangible reason to use these compared to attys in the 3 to 3.5 ohm range?
The answer to your first question is yes. According to Ohms Law, as long and sufficient Amps are available to drive any given combo (Which Darwin DOES provide):
Voltage (E): 7.9 Volts
Current (I): 1.6 Amps
Resistance (R): 5 Ohms
Power (P): 12.7 Watts
For the second part, this is a matter of subjective personal preference. While electronically speaking watts are watts, some will argue (me included) that there IS a difference in vaping lower resistance watts vs higher resistance watts. IMHO, LR watts heat much faster. Even tho electronically watts are watts, in vaping watts express as heat and we are essentially cooking the juices. The various ingredients in the juices can each react/respond differently to various heat levels. VG burns at lower temps than PG - for example. Fruity flavors can respond differently to heat than tobacco flavors, etc. Some juices are more complex combinations of various flavors. If you try a combo flavored juices, especially in a standard or higher Ohms atty/carto (2.2Ωs or higher), try setting your Darwin to 7-7.5 Watts, then vape (with everything else exactly the same) at 8.5-9 watts, and then again at 9.5 thru 10 watts. Obviously the temperature of the vapor and TH will change but you may also notice that at various levels different flavors become more dominant. For example, I used to vape a variety of tobacco menthol juices. I would often find that in the 7.5 watts range the tobacco flavors were more dominant, in the 8.5 range the mixture came thru more well balanced and at the higher 9+ range the menthol became increasingly more dominant.
For me, LR gear seems to heat more quickly - too quickly (for my preferences). I often multi-hit and find that LR can give me a burnt taste too quickly. Also, as LR does heat the coil faster, if I use cartos and multi-hit, the coil can heat faster than the carto can wick the juice (especially when carto gets down to half full or less) and can begin to burn the filler material more quickly. Once carto filler starts to burn, the carto will never taste the same - this is why some post about cartos starting to taste badly after a few re-fills (they are waiting too long to refill and starting to burn the filler.
So, to complete your answer, I prefer to vape 3Ωs range at 8.5 watts much more than LR 8.5 Watts. You can experiment for yourself, and with Darwin this is super easy. Just make sure you are keeping the model of atty or carto the exact same - only using various Ωs levels and also keep the watts setting and juice exactly the same too. When making any comparison of any single component in vaping - to isolate that one component you MUST keep ALL other variables as consistent as possible. So, keeping watts fixed, model of atty (510, 901, 801, etc.) the same, use the same juice and various Ωs rated attys/cartos (same brand too - E.g. Boge 510 carto at 2Ω vs Boge 510 carto at 3Ωs). Going to 5+Ωs may or may not produce a difference discernible enough for you to appreciate the additional difficulty and potential added cost of
using finding and buying those super high Ωs levels. As I said - all subjective and very personal preference oriented. As with EVERYTHING vaping related, there is no "better/best"; there is only YOUR "better/best"
Hope this proves helpful.