UK had 1st Oil Vaping-Related Death in 2010, US has 17th.

[iVapeDIY]

Now 29 ...

• Vaping death toll rises to 29 and cases of mysterious diseases surge to 1,300
• Vaping Illness Tracker: 1,299 Cases and 29 Deaths
• Vaping Illnesses Climb Upward, Nearing 1,300 With 29 Deaths

The outbreak of lung illnesses linked to vaping grew by more than 200 cases in a week, now totaling 1,299, the Centers for Disease Control and Prevention reported on Thursday.

Twenty-nine people have died from vaping-related illnesses, health officials said.
The figures mean that 219 new cases and seven new deaths were reported.​

The current fatality rate, 2.23%, is worse than measles.
Measles rarely kills in the US -- but when it does, this is how it will happen - CNN

 

[Rossum]

The current fatality rate, 2.23%, is worse than measles.

I guess we should all just go back to smoking, it's probably safer.

 

[Jebbn]

Im sure there will be more deaths and illness from using illicit thc cartridges etc.

 

[iVapeDIY]

Now 33 ...

• Vaping Outbreak Death Toll Reaches 33

The CDC is currently performing lab tests of lung biopsies and tissue specimens from patients, as well as conducting "aerosol emission testing" of e-cigarette products used by patients in an effort to uncover the chemicals contributing to the outbreak, the agency said.​

• https://www.washingtonpost.com/heal...s-rise-officials-expand-lab-testing-cdc-says/

Announcing the latest increase in illnesses, the CDC reiterated its conclusion that products containing THC, the psychoactive component of marijuana, are a main culprit and should be avoided. About 78 percent of patients say they used vaping products containing THC, according to the CDC, and nearly a third of patients reported using only THC products. Ten percent said they vaped only nicotine, although doctors caution that people may be reluctant to admit to using marijuana.

The CDC has spent the past few weeks testing patients’ lung biopsies and autopsy specimens and is validating tests for urine and elements of blood as well as fluid squirted into and then collected from the lungs.

Those newer tests, for which the CDC says it already has samples, will help the agency look for substances such as vitamin E acetate, a chemical found in marijuana products that’s drawn investigators’ scrutiny and can be dangerous to inhale. Cheaper than THC oil, vitamin E acetate is often added to vape cartridges, industry experts say.​

• 13-year-old is the youngest of 33 Americans killed by vaping | Daily Mail Online

A 13-year-old has become the youngest person to die of vaping-linked illness, underscoring the outsize and devastating effects e-cigarettes are having on American youth as US officials try to keep kids away from them.​

 

[Katya]

I guess we should all just go back to smoking, it's probably safer.

I wouldn't go back to smoking quite yet.

Effects of Electronic Cigarette Constituents on the Human Lung: A Pilot Clinical Trial

There were no significant differences in changes of BAL (bronchoalveolar lavage) inflammatory cell counts or cytokines between baseline and follow-up, comparing the control and e-cig groups. However, in the intervention but not the control group, change in urinary PG as a marker of e-cig use and inhalation, was significantly correlated with change in cell counts (cell concentrations, macrophages, and lymphocytes) and cytokines (IL-8, IL-13, and TNF-α), although the absolute magnitude of changes was small. There were no significant changes in mRNA or microRNA gene expression.

It's a small pilot study from Ohio, and they only tested PG and VG (no nic and no flavorings), but they found nothing, nada, zip, zilch, nil, naught, Nichts. A tiny increase in inflammation is truly insignificant in comparison to smoking. I'm pretty sure that breathing LA air on smoggy day causes much more significant lung inflammation.

So, at least for now, we can breathe easier (pun fully intended). And I hope that CDC finds out what the heck is going on before the whole world bans vaping.

 

[plumeguy]

No one in the history of ever uses the term "e-cigarettes" to refer to THC vape pens.

Unless they are trying to confuse, deceive, and con the intended recipient.

 

[AttyPops]

Now 33 ...

The #'s in the articles are all over the place.

I'm going with the CDC's latest info, that "only" 10% reported exclusive nic use. The remainder were "various substances" not nic vaping. (I also assume some of that 10% lied due to local laws or street deals).

It's interesting:

What We Know

• As of October 15, 2019, 1,479* lung injury cases associated with the use of e-cigarette, or vaping, products have been reported to CDC from 49 states (all except Alaska), the District of Columbia, and 1 U.S. territory.
• Thirty-three deaths have been confirmed in 24 states.
• All patients have reported a history of using e-cigarette, or vaping, products.
• We do know that THC is present in most of the samples tested by FDA to date, and most patients report a history of using THC-containing products.
• The latest national and state findings suggest products containing THC, particularly those obtained off the street or from other informal sources (e.g. friends, family members, illicit dealers), are linked to most of the cases and play a major role in the outbreak.
• As such, we recommend that you should not use e-cigarette, or vaping, products that contain THC.
• Since the specific causes or causes of lung injury are not yet known, the only way to assure that you are not at risk while the investigation continues is to consider refraining from use of all e-cigarette, or vaping, products
• The use of e-cigarettes, or vaping, products is unsafe for all ages, including youth and young adults. Nicotine is highly addictive and can harm adolescent brain development, which continues into the early to mid-20s.

Among 849 patients with information on substances used in e-cigarette, or vaping, products in the 3 months prior to symptom onset**:

• About 78% reported using THC-containing products; 31% reported exclusive use of THC-containing products.
• About 58% reported using nicotine-containing products; 10% reported exclusive use of nicotine-containing products.

From here with more info: Outbreak of Lung Injury Associated with E-Cigarette Use, or Vaping

 

[iVapeDIY]

I'm going with the CDC's latest info, that "only" 10% reported exclusive nic use. The remainder were "various substances" not nic vaping. (I also assume some of that 10% lied due to local laws or street deals).

Yup. Interestingly, many EVALI cases (non-THC) are linked to severe asthmatic/ allergic reactions.

• More evidence that e-cigs cause asthma on top of the effects of smoking cigs | Center for Tobacco Control Research and Education

The odds of having asthma are increased by about 50% among adolescents who are using e-cigarettes, controlling for cigarette smoking and other risk factors.​

• E-cigarette use and asthma in a multiethnic sample of adolescents - ScienceDirect

We conclude that e-cigarette use by adolescents is independently associated with asthma.​

• U.S. Rep. Diana DeGette Decries Lack of Vaping Oversight

Locally, Colorado experienced its first death due to a vaping-related illness on Oct. 3, the very morning of the Science Policy Summit, in an 18-year-old vaping user with a history of asthma.​

• How Juul Hooked Kids and Ignited a Public Health Crisis

Jami Scheetz’s 15-year-old son Devon, who has severe asthma, kicked a brutal vaping habit over the summer, with help from a nicotine patch. But as soon as school started and he was once again around kids vaping, his habit returned. On Sept. 12, Devon vaped at school and immediately began sweating and vomiting.​

• JUUL Is Facing a New Lawsuit from a Dead Teen's Mother

Vail's lawyers insisted Wakefield's asthma was not a persistent problem in his young adult life, and that Wakefield didn't even really use an inhaler. (The lawsuit itself cites studies that have claimed e-cigarettes could possibly cause—or at least exacerbate—asthma.) ​

Imaging of Vaping-Associated Lung Disease
https://www.nejm.org/doi/full/10.1056/NEJMc1911995

Through clinical and pathological investigations, patterns of giant-cell interstitial pneumonia, hypersensitivity pneumonitis, and diffuse alveolar hemorrhage were identified

Although the variety of imaging patterns suggests different mechanisms of injury, and more patterns will probably be reported, most of the patterns have basilar-predominant consolidation and ground-glass opacity, often with areas of lobular or subpleural sparing. Rapidly developing acute lung injuries (e.g., acute eosinophilic pneumonia and diffuse alveolar damage) are associated with inhalational injuries and have overlapping pathological and imaging findings,5 and they have been reported to occur with vaping.1 Hypersensitivity pneumonitis is an immune response to an environmental antigen, but the antigens related to vaping are unknown. Lipoid pneumonia is an inflammatory response to the presence of lipids within the alveolar space and typically results from aspiration of hydrocarbons or oil-based products, but it has now been seen with vaping. We have not observed the computed tomographic finding of fat attenuation in the lung, which is a hallmark of lipoid pneumonia, in these cases of vaping-associated lung injury. Not all cases are acute; organizing pneumonia often develops subacutely, over a period of days to weeks, and the one case of giant-cell interstitial pneumonia (a rare fibrosing interstitial lung disease) that was correlated with hard metals in ENDS developed over a period of 6 months.​

The parallels to severe allergic reaction to benzoates (used for enhanced nicotine absorption and preservative) are striking.

 

[iVapeDIY]

Now 35 ...

• Vaping-related lung injuries rise to 1,604 cases nationwide, CDC says - CNN
• Vaping has killed 35 Americans and sickened more than 1,600, CDC says | Daily Mail Online
• District of Columbia reports first death from vaping disease
  
• Vaping death toll reaches 35 as epidemic of e-cigarette lung disease spreads to more than 1,600 victims

 

[virm]

(not sure if this thread concerns only anglo-world cases; video there for reference. they'll throw in a couple of pinches of english, to make doctors' pretentiousness really pop)

new (actually not sure of broadcast date, but posting is from a couple months ago) case of pulmonary hemorrhage in Amman (that's where the broadcast is from, anyway) (guess translation).

The three in program are physicians, including the injured lad. he had the bleed working at a hospital and passed out. interview is month thereafter. ex-smoker (changed to) > casual smoker > exclusive vaper (mod > pod, 30-50mg (nicsalt, obv.)
the elder recounts several studies, incl. European respiratory assosiation and a ban in norway and oz, his info on studies are more uptodate, though probably incomplete, than banning-news (unless these places have renewed a ban). says the '95% safer'-thing is not exactly a study, just an estimate, this would change now, but comprehensive study is difficult.

FYIs,
cannibus is illegal there
the program did previously make pro-vaping episodes, also hosting elder physicians.
regulations are still not drawn up so there's probably little control on liquids etc. (the elder actually states he is trying to counter the current ~move toward regulation/legistlation, which we're starting now as other countries are starting to ban~
he does mention some of the regular irrelevant stuff, like the underage vaping crap and the rest the US mess
does not mention cannibus, thc, or the specifics of the global cases



there's something i found from cairo too, but it's less to the point, more debate-like.

among the reads i've caught this was more recent and clearer, it's pop-science, mentions the US-bla too, and probably only summarizes parts of what's already been psted here, but here it is.

Here Are All The Valid Health Reasons Why So Many Countries Are Banning Vapes