Yes, that does make a difference. I have added 100mg nic to most of the NT lineup at one time or another. With super thorough shaking and additional steep I have not noticed a change of flavor at all. In fact, I have reduced NT juices nic levels by mixing in 1 part 50/50 PG/VG to 2 parts NT juice and with 2 - 4 weeks additional steep I could not tell the difference.
But then again your a Penguin...you eat raw fish all the time!.....LOL
Just funn'in...no insult intended!