Thank you Hula. You are correct. The problem is the MDR1 gene. You can have your dog tested for it, for 60 dollars. It effects herding dogs. The GSD doesn't have it nearly as much as the Aussie does. I warned the vet about this, and just said treat her like you would, if you knew she had that gene. Better safe, than sorry. This is why I was perturbed that they gave my dog another flea med, on top of the one I had just given her. I have been watching her closely, and she is doing fine so far. If the Frontline doesn't work, she won't get another flea med until that full months time is up. You also have to be careful with some flea meds, because they can kill your cat too, if your cat is pals with your dog. So far I don't have that problem. Neither cat is cozy with my puppy. I hate bloodsuckers of any type. ( That means fleas, ticks, and mosquitoes. ) I remember giving dogs a powder flea med, when I was a kid. The dogs hated it. They would shake, and a cloud of dust from it, would go all
through the air. The once a month deal is very nice. You don't usually have to strong arm a dog, to get it on them, like you did with that flea powder back in the day....
Be real careful on switching flea meds for German shepherds or other herding dogs. - For example:
Parasiticidal drugs, especially the avermectin group of dewormers: ivermectin (Heartguard�), selamectin (Revolution�), milbemycin (Interceptor�), and moxidectin (ProHeart�) may result in toxicity of the central nervous system when given above therapeutic levels.
Also ensure you're using the Vet's brand as the store bought brands are not nearly as effective.