Hi, and some MSDS data on PG

[nomadman]

I have been vaping for about a month now and it has mostly been a good experience so far. The only side effects I am having is an increase in shortness of breath. I am sure it is from vaping because I know my body and I have been using nicotine lozenges for 4 years, only smoking analogs a week here and there, and the same thing happens after a few days of smoking tobacco.

I picked up the e cig because I thought that it would be a safe alternative ( at least no worse than the lozenges) to keep me off analogs for good.

I have read a lot of comments about how PG is safe. None of the comments were backed up with data or studies so I did some research and came to a different conclusion. According to my findings there is no scientific evidence that PG is safe. In fact, the evidence indicates that PG is indeed toxic and the prolonged exposure can cause the body harm.

I searched Google Scholar with the terms "propylene glycol" and "toxicity" and then "propylene glycol" and "lactic acidosis", and also had a look at the MSDS.

This is an excerpt from the MSDS :

Potential Chronic Health Effects:
The substance may be toxic to central nervous system (CNS). Repeated or prolonged exposure to the substance can produce target organs damage.



Here is the link to the full MSDS

http://www.sciencelab.com/msds.php?msdsId=9927239


That makes to answer to the "Is PG bad for you?" question clear to me, yes PG is bad for you. I am pretty sure that vaping the stuff would fall under "repeated and prolonged exposure".

I also found a few peer-reviewed articles on Google Scholar indicating that PG can cause lactic acidosis.

Lactic acidosis can cause nausea, abdominal pain, anxiety, irregular heart rate, and tachycardia (panic attack anyone?) Source: Lactic Acidosis - Symptoms - Better Medicine

Links to a few of these articles are here ( these are from 1985 to 2005, so there is recent evidence to support this):

Propylene Glycol-Induced Lactic Acidosis in a Patient with Normal Renal Function: A Proposed Mechanism and Monitoring Recommendations

Cookies Required - CAB Direct

ingentaconnect Propylene Glycol as a Cause of Lactic Acidosis

I hope this post helps others who were looking for some straight answers such as myself. Just because someone with a vested interest, or someone who thinks they know a "fact" because they read it on a forum or wiki, says a product is safe does not make it so. For this reason I took the time to provide links to the information I presented.

I do have some VG juice on the way, but if the breathing issue keeps up I may just stick with the lozenges and use my e-cig when I really need to smoke (after a few beers).

 

[Mystified]

For every negative report on PG you will find an equal amount of research that notes it is not harmful...keep researching and keep vaping...good luck

 

[nomadman]

For every negative report on PG you will find an equal amount of research that notes it is not harmful...keep researching and keep vaping...good luck

Hi and thanks for the response. Would you be so kind as to post links to the research you mentioned that contradicts the findings I posted. I got the feeling that, because of the time span of all the studies I looked at, these findings were well established in the literature and not being refuted.

Thanks

 

[Nicko]

It GRAS. Generally recognised as safe by the FDA. I heard about studies that prove water is dangerous. Do you drink it?

 

[Alac]

Ok, PG is known to affect cats on a spicies specific way.
The food they few the cats was 41% PG, thats almost half the weight of thier food was PG.
And we wonder why the cats got sick.

Lesson learned?

Maybe we shouldn't let our cats puff on PVs.

 

[nomadman]

Where does it say it is GRAS to repeatedly, over a long period of time, directly inhale vaporized PG? I would genuinely like to know.

 

[BardicDruid]

Now to pick you stuff apart, that the first time I've ever seen an MSDS from a chemical company for propylene glycol, all the ones I've seen are from pharmaceutical manufactures. Propylene glycol is the main ingredient used in most liquid medications and inhalers, both are FDA approved for internal use. As for the rest you need to really read them, the aliment your talking about is from INJECTED use, not inhaled. If you search the net hard and long enough you can find whatever you want the way you want it.

 

[DLite]

Now to pick you stuff apart, that the first time I've ever seen an MSDS from a chemical company for propylene glycol, all the ones I've seen are from pharmaceutical manufactures. Propylene glycol is the main ingredient used in most liquid medications and inhalers, both are FDA approved for internal use. As for the rest you need to really read them, the aliment your talking about is from INJECTED use, not inhaled. If you search the net hard and long enough you can find whatever you want the way you want it.

Agreed 100% , I was going to say if its so "Bad" for us over a long period of time, why is it in numerous foods you eat and why is it prescribed medications such as inhalers and such????

 

[nomadman]

Ok, PG is known to affect cats on a spicies specific way.
The food they few the cats was 41% PG, thats almost half the weight of thier food was PG.
And we wonder why the cats got sick.

Lesson learned?

Maybe we shouldn't let our cats puff on PVs.

Well, I see so many pro PG post quoting studies conducted on monkeys and rats. I guess that is only OK if it supports your opinion. I am not looking for opinions, but facts. I seems to me the blind is leading the blind.

 

[Nicko]

You should consider yourself honoured to be a willing participant in this uncontrolled experiment. Without us, nobody will ever know the long-term effects of vaping. The alternative is for smokers to keep lighting up their cigs. And we all know the long term effects of that.

 

[DLite]

(after a few beers).

Why are you so concerned with the effects of PG when your destroying your liver. Have you looked up the effects of alcohol on your body???? I mean if your concerned with what you do to your body.

 

[Alac]

Medicine: Air Germicide - TIME

The studies were done in 1942, they kept primates for months in an atmosphere with PG mist.
Result? They got healthy.
from this article..
"So far, after many months' exposure to the vapor, the monkeys are happy and fatter than ever."
This was in addition to helping protect the primates and rats from airborne ailments.

The only fear was PG "pooling" in the lungs, later studies showed this was not an issue.

 

[progg]

Here's a link to PG studies :


National Vapers Club - Meeting Place for lovers of e-cigarettes, personal vaporizers and all things "fog" producing!

 

[dormouse]

Hospitals use PG vapor to deliver drugs via inhalation therapy, even to lung transplant patients

Concert fog is also PG

 

[Alac]

Well, I see so many pro PG post quoting studies conducted on monkeys and rats. I guess that is only OK if it supports your opinion. I am not looking for opinions, but facts. I seems to me the blind is leading the blind.

Your study only deals with cats.

On the other hand, we also have over 50 years of PG being used in theactical smoke.
Actors, magicians, and DJs at night clubs have been standing in an atmosphere of the stuff for decades.

Difference? We typically only vape Medical grade PG, not the junk from the smoke machines.
`

 

[nomadman]

Now to pick you stuff apart, that the first time I've ever seen an MSDS from a chemical company for propylene glycol, all the ones I've seen are from pharmaceutical manufactures. Propylene glycol is the main ingredient used in most liquid medications and inhalers, both are FDA approved for internal use. As for the rest you need to really read them, the aliment your talking about is from INJECTED use, not inhaled. If you search the net hard and long enough you can find whatever you want the way you want it.

I did read them. And I know that inhaling a chemical only second to injecting a chemical with respect to how quickly it enters and affects your body. I am sure you can draw the parallel.

The studies indicate to me that PG is not as safe as some forum members are making it out to be. I think the truth is we don't truly know is it is safe to use it in the manor that we are using it.

While PG may be approved for meds and as a food additive, the FDA is obviously curious, as am I, as to what the effects of LT use of e cigs are. Funny how people both hide behind, and berate, the FDA at the same time. Keep in mind that there are many drugs that the FDA one approved, only to repeal said approval.

BTW, using Google Scholar is very different than "searching the net", and I am not one to cherry pick my data.

 

[nomadman]

Alac,

You only looked at one study.

 

[nomadman]

Why are you so concerned with the effects of PG when your destroying your liver. Have you looked up the effects of alcohol on your body???? I mean if your concerned with what you do to your body.

I really don't drink that much, not enough to affect my liver by any means . I was an EMT many years ago and I am well aware of the effect alcohol has on the body. Thanks for asking.

 

[Nicko]

You said you have some VG on the way. Do you have hard scientific proof that it's 100% safe to inhale it long term?

 

[colt45]

it sounds as if your mind is made up and your trying to convince us instead of yourself .
perhaps you should not vape if that is your belief.