Hi, and some MSDS data on PG

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DLite

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Is that study showing the effects of vaping PG or VG in general. Only reason I ask is because you should talk with a Doctor because both PG and VG are in many vaporized medications and if it was that harmful to your body they wouldnt prescribe them.

Have you looked into any studies of Nicotine Lozenges???? or what chemicals are used in them??
 
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nomadman

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Is that study showing the effects of Vaping PG or PG in general. Only reason I ask is because you should take with a Doctor because both PG and VG are in many vaporized medications and if it was that harmful to your body they wouldnt prescribe them.

Have you ever read the list of side effect on most medication?
 

nomadman

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You said you have some VG on the way. Do you have hard scientific proof that it's 100% safe to inhale it long term?

Nope, but I have not found any research that indicates it is harmful either. I am trying VG because of the shortness of breath that vaping is causing me. I know that that can be a side effect of PG.
 

Xaria

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I have tried other ways to quit smoking and they did not work. I know for a fact cigarette smoking would of killed me. Either by cancer or COPD, which I have 2 parents who are currently dying from this. Now if there is a slim chance this PG is going to kill me later on. I will gladly take the death from PG over cigarettes.
 

salemgold

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I smoked cigs for 36 years. I have been vaping for 1 year. I know from the way that I am breathing better and feel better in general that vaping is much healthier than smoking cigs. So my personal choices are to know the damage that I am doing to my body and go back to smoking cigs. Not be able to catch my breath and all of the other negative effects of smoking. Or I could just keep vaping and continue to feel healthier and not get winded just walking up a flight of steps. IMO it is a no brainer.
Will I feel better knowing the long term effects of vaping? Yes and I am sure that many of us will. I have tried many other methods to stop smoking and have failed. This method works. So I will take my chances while breathing better and feeling better with vaping before returning to what I know will kill me eventually and make me feel and smell bad along the way :) JMO
 

Alac

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Alac,

You only looked at one study.
You really only posted one study.

The other things you posred are about people the recieved PG intraviniasly (one was stated for 18 days).
So, a mass amount of PG was injected in thier body, and then they were tested for PG in thier body fluids.
Sounds like a reasonable outcome.
 

Mindfield

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Nope, but I have not found any research that indicates it is harmful either. I am trying VG because of the shortness of breath that vaping is causing me. I know that that can be a side effect of PG.

PG is a synthetic glyceride, and none of the tests you've linked to are conclusive. Maybe there are no hard facts on long-term inhalation of PG or VG, but you know what? I couldn't possibly care less. Nobody (except those with a PG allergy) here has reported any negative effects from vaping other than some experiencing dry mouth/sore throat, and that only because PG and VG are both very hydrophilic, so that's to be expected. And of course those who OD a bit on nicotine, for those that vape nic-based liquids. I started smoking on a much flimsier basis.

E-cigs let me quit smoking where nothing else did, and I haven't had a single problem to report that wasn't related to bad juice. I've been 4 months now without a cig and that's awesome. Many others here have been much longer. We're all doing fine, thanks.
 

WomanOfHeart

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This is from one of your articles:

"After 18 days of high-dose continuous infusion of lorazepam (maximum dose 50 mg/h), the patient developed severe lactic acidosis secondary to propylene glycol toxicity, the main diluent of lorazepam."

This patient received extremely high doses of IV lorazepam which caused the lactic acidosis. I don't think the same thing can be said of PG when it's vaped. The other studies you posted regarded giving extremely high doses of PG to cats. Cats have different digestive systems from humans and are more sensitive to PG than humans.

I really don't think what you've posted is applicable to vaping. Plus, there's a HUGE difference between Industrial PG and Food Grade PG, which as others have pointed out is GRAS.

Have you actually tried vaping? If not, then why make this alarmist post? It really does sound like you're trying to convince yourself because you certainly aren't convincing me. There are plenty of folks here who have been vaping for a couple of years with no ill effects.
 

tiffytiff

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LMAO define "fine" :) JK!
PG is a synthetic glyceride, and none of the tests you've linked to are conclusive. Maybe there are no hard facts on long-term inhalation of PG or VG, but you know what? I couldn't possibly care less. Nobody (except those with a PG allergy) here has reported any negative effects from vaping other than some experiencing dry mouth/sore throat, and that only because PG and VG are both very hydrophilic, so that's to be expected. And of course those who OD a bit on nicotine, for those that vape nic-based liquids. I started smoking on a much flimsier basis.

E-cigs let me quit smoking where nothing else did, and I haven't had a single problem to report that wasn't related to bad juice. I've been 4 months now without a cig and that's awesome. Many others here have been much longer. We're all doing fine, thanks.
 

dormouse

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Just FYI - PG is thin and lets through the most flavor and also the most of nicotine's TH and skin irritation. Nicotine is a skin irritant. Medium and high nicotine in 100% PG can be irritating. it can cause sore irritated tongue, mouth, throat, sinuses and even lungs. Even nicotine patches warn of skin irritation.

VG is thick and dulls/smooths everything PG lets through, but alone and unthinned is too thick for many methods of vaping (cartomizers, tanks).

Most people use a blend - have some VG in the ratio of the base liquid moderates the irritation and adds thicker vapor. I use 80PG/20VG in cartomizers for good wicking. Many like 50/50 in atomizers - smoother with lots of vapor. etc. When I started vaping, 18mg in 100% PG made my tongue sore and numb. 18mg in 70PG/30VG did not.
 

Mindfield

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This is from one of your articles:

"After 18 days of high-dose continuous infusion of lorazepam (maximum dose 50 mg/h), the patient developed severe lactic acidosis secondary to propylene glycol toxicity, the main diluent of lorazepam."

This patient received extremely high doses of IV lorazepam which caused the lactic acidosis. I don't think the same thing can be said of PG when it's vaped. The other studies you posted regarded giving extremely high doses of PG to cats. Cats have different digestive systems from humans and are more sensitive to PG than humans.

I really don't think what you've posted is applicable to vaping. Plus, there's a HUGE difference between Industrial PG and Food Grade PG, which as others have pointed out is GRAS.

Have you actually tried vaping? If not, then why make this alarmist post? It really does sound like you're trying to convince yourself because you certainly aren't convincing me. There are plenty of folks here who have been vaping for a couple of years with no ill effects.

And those have to be extremely high doses, too. The MSDS sheet linked on the LD50 of PG:

Toxicological Data on Ingredients: Propylene glycol: ORAL (LD50): Acute: 20000 mg/kg [Rat]. 22000 mg/kg [Mouse].
DERMAL (LD50): Acute: 20800 mg/kg [Rabbit].

20,000mg/kg minimum for a small animal for 50% of the test group to die from PG toxicity. Put another way, using that figure, if I was part of test group of 100 people testing for PG toxicity, in order to have a 50/50 chance of dying from it, I'd have to ingest 1,540,000mg of PG. 1.54 kilos. 3.4 pounds. In one sitting. I vape about 3ml a day. I think I'm probably rather safe.
 
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