Sure, you can do it. Buy some low concentration e-liquid (Slightly stronger than what you vape now) for practice in mixing and measuring the first couple of times. I wouldn't work with the stronger e-liquids like 100 mg until proficient with the lab techniques. Plenty of details in the DIY section.
I have enough nicotine base in the freezer to last me another 18 months, at least.
Sorry, but I'm going to disagree here.
Lots of people start out with the low concentrates when getting into DIY and I recommend recommend against it in every case.
The reason I disagree is a simple matter of cost. 100mg/ml Nicotine goes further than 48mg/ml (or whatever). Although it may be slightly more dangerous to handle the higher concentrate, it's not like you're dealing with 100% pure Nicotine. It's still diluted to a generally safe mixture.
100mg/ml Nicotine is no more hazardous than many of the common household chemicals we all have in our cabinets (ie. Chlorine Bleach, Ammonia, Toilet Cleaner, CLR, etc.). Just use common sense when handling it. Again...we're not talking about 100% pure Nicotine here. Pure Nicotine would require a proper laboratory and safety equipment that most of us don't have in our homes.
My first DIY purchase was for 250ml of 60mg/ml and I quickly came to regret the decision. It went quickly and within a couple weeks I was re-buying.
Buy the stronger concentrate from the start and buy as much as you can. Even if it's left in a closet, it will last a LONG time...freezing it will make it last even longer. It may turn yellow, this is normal and won't hurt a thing.
Get a good calculator (such as the one from
Welcome to Ahlusion) and wear latex or vinyl gloves when handling. It's also not a bad idea to wear safety goggles to avoid eye contact if it splashes. Keep away from children and pets, and always make sure your DIY supplies are clearly marked with labels of some kind so there's no confusion or accidents.
Be sure to stick to the recipe in the calculator! Check and re-check your measurements and you will have no problems
With a little common sense and safety measures, there's no more danger from 100mg/ml Nicotine than most of the other chemicals in your home. It's the cheapest way to go when DIY.