Laboratory study needs experienced electronic cigarette users

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rothenbj

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Jul 23, 2009
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Any results or info about this study? I have not began vaping yet and really am trying
to learn as much as possible about safety before starting. I am not a current analog smoker so being safer then analogs has no meaning to me.

Perhaps being a non-smoker you might get meaning from this. Why in the world would you want to start vaping? It costs money, it takes time, it's not considered cool. Why would you even consider it.

*edit after reading other posts*

Let's see if I have this right. 2 and a 3 year old that you provide daddy day care for while your wife works (no problem, not traditional, but it's a new world) Wife may get laid off in August due to a merger, it happens. Quit smoking five years ago cold turkey, admirable. What the H are you thinking?

Nuff said, just my humble opinion.
 
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Vocalek

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So i wonder what type of study they did or are doing.


They are trying to verify whether experienced users are getting nicotine from their e-cigarettes. It is unknown how Eissenberg plans to interpret the results they get.

Their first e-cig experiment involved novice users, measuring blood levels of nicotine after 10 puffs from an e-cigarette. Before all the data was gathered, Eissenberg sent a letter to the editor of Tobacco Control announcing that e-cigarettes do not deliver nicotine, and postulated which most readers interpreted to mean that because of this, that e-cigarettes are unlikely to be helpful in quitting smoking.

Eissenberg reported preliminary results for this new study at the annual conference of the Society for Research on Nicotine and Tobacco. This was a brief report called a "poster" and the results involved only three subjects. There is a discussion elsewhere in ECF.

http://www.e-cigarette-forum.com/fo...nbergs-study-yep-e-cigs-deliver-nicotine.html
 
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teissenb

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Jun 2, 2009
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Elaine:

Below I have reprinted the entire discussion section of the TC letter. Can you please tell me where I said that ECIGs would be "unlikely to be helpful in quitting smoking"?

Tom E.

PS: A short report describing the current "experienced users" study has been revised to address reviewers' comments and is now under re-review...


"Relative to a tobacco cigarette, 10 puffs from
either of these electronic nicotine delivery
devices (E-cigarettes) with a 16 mg nicotine
cartridge delivered little to no nicotine and
suppressed craving less effectively (see Bullen
et al).6 Importantly, these results were from
two specific products tested under acute
conditions in which puff number was
controlled. Variability in product design may
influence vapour content7 and chronic use
and/or more intensive puffing (ie, more puffs,
greater puff volume) may influence nicotine
delivery. Given these and other factors, there
is an ongoing need to evaluate electronic
nicotine delivery devices (E-cigarettes). These
evaluations should be conducted in a manner
that takes into account variability in design
(including cartridge nicotine content),
examines the effects of user behaviour over
time and compares these products to existing
methods of delivering therapeutic nicotine
safely and effectively. Taken together, the
well known lethality of nicotine, variability
in cartridge/vapour content,7 and the
results reported here all support the notion
that electronic nicotine delivery devices (Ecigarettes)
and their nicotine-containing
solution should be evaluated, regulated,
labelled and packaged in a manner consistent
with cartridge content and product effect. At
the least, consumers should be aware that,
unlike several regulated nicotine products
(eg, gum,8 patch9), these putative drug
delivery systems do not delivery nicotine
effectively after acute administration."




They are trying to verify whether experienced users are getting nicotine from their e-cigarettes. It is unknown how Eissenberg plans to interpret the results they get.

Their first e-cig experiment involved novice users, measuring blood levels of nicotine after 10 puffs from an e-cigarette. Before all the data was gathered, Eissenberg sent a letter to the editor of Tobacco Control announcing that e-cigarettes do not deliver nicotine, and postulated that, because of this, e-cigarettes are unlikely to be helpful in quitting smoking.

Eissenberg reported preliminary results for this new study at the annual conference of the Society for Research on Nicotine and Tobacco. This was a brief report called a "poster" and the results involved only three subjects. There is a discussion elsewhere in ECF.

http://www.e-cigarette-forum.com/fo...nbergs-study-yep-e-cigs-deliver-nicotine.html
 

Ande

Super Member
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Mar 27, 2011
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Hey Dr E-

Not much time to quote hunt at the moment, but will try later. I think the "just like puffing on an unlit cigarette" line, widely attributed to you, is one of the things that gave the impression that your research led you to conclude ecigs were unlikely to help smoking cessation.

I don't even know if that's something you've said, or to whom. If you're being misquoted, I know that's a pain.

Best,
Ande
 

Vocalek

CASAA Activist
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ECF Veteran
Dear Tom: I have edited my post to remove the attribution to you for "unlikely to be helpful in quitting smoking." You are indeed, correct, that the phraseology does not appear in your letter. But somehow the idea of "delivers no nicotine" and "unlikely to help people quit smoking" got married in my memory. How did that happen?

I did some searching and found that you did not make that direct statement in the press release issued by VCU either. Yet I could swear that I read it somewhere...

The VCU press release quoted you: "It’s not just that they delivered less nicotine than a cigarette. Rather, they delivered no measurable nicotine at all. In terms of nicotine delivery, these products were as effective as puffing from an unlit cigarette.”

I have never seen success rate statistics for that method. My guess would be that it's not highly effective. Be that as it may, I continued searching and did track down the source.

Given that it delivers almost no nicotine, it follows that the E-cigarette is unlikely to be effective in reducing nicotine withdrawal symptoms and helping addicted smokers to quit in the long run.
E-cigarettes deliver almost no nicotine. | Freedom From Smoking | Healthline

The writer was Jonathan Foulds, a respected smoking cessation researcher himself.
 

Russ 78

Moved On
Nov 17, 2011
51
26
Missouri,U.S
Sup vapers ok hears my :2c: I have bin a smoker for 21 years I started at 1 or 2 a day and was abol to smoke 1 and evan 2 packs a day, 2 if under stress( I have a disorder panic attacks so the nick levels in my body in some situations gos very high and the cravings are not pleasing. the gum, all the cheep patches, and the Dtox did not work. but the Dr's perscribed patches did, I smoked dearing use with no nic buzz at all no quizy feeling or calming ex for whin i finiched at lest 2 or 3 cigs, Now learning about nic transferince in a vapor was very intresting, looking to vaperisers for things like respotery illness, and the fog makers and the usees good and bad and all the other uses were very promising. So investing in to a cheep $25 kit E-cig at 1.8mg 3.5v with a 2.0ohm atty poly fill carto, I did my own clincal tryal dearing a very stressfull day I smoked 2 cigs to satisfy a craving and felt calm and relaxed, I then wated for a craving atack and atempted to repres the craving for 2 hours I then used the e-cig for the first time i took 5 slow deap inhals and put it down the flavor and over all experince i did not like but I did not want a cig after I did recive a nic buzz I then wated for a craving attac it was a little soner than usuly about 30 min but it did deliver a nic dose so I then vaped like a fratetrane untill i felt quizy like back in the day whin I first started smoking. This was the all the profe i neaded. Now the 1.8 did not cintinu to satisfy my cravings after a munth or two I had to expermint with 36mg and cutting it down to 25mg and trying to ballince the nead to puf more than once with out the quizy feeling or a nic over dose( vomiting shaking) so this was my personal studdy using my self as a guniepig Thank you for reading smoke free for 4 months no bronkeal inflamation for 3 months
 
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