I have 1.5 liters in my freezer now. I started at 24mg but now I'm down to 6mg. At 6, that should last a long time. But that would be fifty 30ml bottles, and that's a heck of a lot of bottles! If you store in boxes you are either not freezing it or you have quite a large deep freezer without all the frozen food most people stuff in them. And it may be more important to store in the freezer than a couple extra openings. Anyway, the way I threaded that needle is I broke the liters into something like a 500ml bottle, a 250 ml bottle, a 120ml bottle, and a couple 30ml and 60 ml bottles. I keep one 30ml bottle at room temp in a cabinet. My thinking is that, worst case, the NIC will get transferred a couple of times, something like 500ml-->250ml-->120ML-30/60ML over the course of a year or two or more. My sense is that those few pours are not going to degrade things. Now, if I kept a liter or 500ml bottle in a cabinet and drew from it a hundred times, that would be different, and that is what I'm trying to avoid.This is precisely why I store mine in 30ml bottles; I never make much juice at once, and one 30ml bottle of 100mg nicotine lasts me a couple months to use up; i don't want a bottle of nicotine opened more than that. also, the small bottles store very easily; I use the same box they came in, and just stack 'em up. Takes very little space.
Andria
Just my own take on that, with no hard evidence.