We use a window AC unit, 14,000BTU, and it works fairly well cooling the whole house, and most importantly, keeping the humidity down to a comfortable, for here, level. I bought it the day we moved in so it's about even years old now. It's a 120 volt unit but does need a 20 amp circuit, then again it's pretty big for a 120 volt unit. We actually cool the whole space we spend most of out time in with it, maybe 1000sqft total. We use a fan and the quirks of how the house is laid out to do that. I also added a small fan in the "dead spot" of our foyer that would actually get cold to move that air around, too. Electric bills never get over $250 even if we run it 24/7. Having 2x6 heavily insulated walls, a heavily insulated attic and double, insulated glass, windows and doors helps, too.
The thing that bothers me about window units, beside putting them in and taking them out, is that the thermostat is on the unit, itself. That isn't the best solution by far. If it's a little cooler outside, like at night, the thermostat has to be lowered to compensate for the cooler temperature of the case. Why, with the popularity of Bluetooth, the thermostats can't be remoted beats the heck out of me. It has a remote control so adding temperature sensing shouldn't be all that hard. A few bucks more, sure, but well worth the added accuracy and comfort. We keep ours set on "auto" and it does cycle off when it gets cool enough in here.
The thing that bothers me about window units, beside putting them in and taking them out, is that the thermostat is on the unit, itself. That isn't the best solution by far. If it's a little cooler outside, like at night, the thermostat has to be lowered to compensate for the cooler temperature of the case. Why, with the popularity of Bluetooth, the thermostats can't be remoted beats the heck out of me. It has a remote control so adding temperature sensing shouldn't be all that hard. A few bucks more, sure, but well worth the added accuracy and comfort. We keep ours set on "auto" and it does cycle off when it gets cool enough in here.

RIP lil egg
