My opinion? I can't really imagine how you're hurting 'em above 3.0V. Take a look at some of the following spec sheets:
http://www.powerstream.com/p/INR18650-25R-datasheet.pdf
http://www.powerstream.com/p/us18650vtc5-vtc5.pdf
http://www.powerstream.com/p/LG 18650HE2 Technical Information.pdf
Samsung and Sony run 'em down to 2.5V in their life-cycle tests, while LG runs 'em all the way down to 2.0V!
Will you get more cycles by not running them down as low? Maybe. But they would also last longer if you went with a lower charging voltage than the full 4.2V. Personally, I don't obsess over it for a $6-9 battery, and I really like the fact that I can consistently drain a 6ml bottle of juice on a single 18650 in my DNA40 bottom-fed mod.
http://www.powerstream.com/p/INR18650-25R-datasheet.pdf
http://www.powerstream.com/p/us18650vtc5-vtc5.pdf
http://www.powerstream.com/p/LG 18650HE2 Technical Information.pdf
Samsung and Sony run 'em down to 2.5V in their life-cycle tests, while LG runs 'em all the way down to 2.0V!
Will you get more cycles by not running them down as low? Maybe. But they would also last longer if you went with a lower charging voltage than the full 4.2V. Personally, I don't obsess over it for a $6-9 battery, and I really like the fact that I can consistently drain a 6ml bottle of juice on a single 18650 in my DNA40 bottom-fed mod.