FYI Polysorbate 80, in several flavorings

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MonkeyMonk

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Many flavorings contain polysorbate 80. (I've located several at LorAnn's, I have not contacted Bickford. I noticed that several of the flavors containing Polysorbate 80 at LorAnn's are also flavors starting to appear in ejuice flavors.)

Intro: Polysorbate 80 - Wikipedia, the free encyclopedia
Disturbing Scientific Findings: Polysorbate 80 Causes Infertility: An Emulsifier That Can Damage Your Reproductive Health

Highlights of above article:

Put in plain English, polysorbate 80 can affect your immune system and cause severe anaphylactic shock which can kill.

According to the World Intellectual Property Organization, which is part of the United Nations, scientists from the organization are developing vaccines specifically to damage fertility as a method of contraception. A suggested ingredient for the vaccine is tween 80 (polysorbate 80):


Polysorbate 80 is in shampoo and bubble bath, and the dairy industry uses it in ice cream to help retain the shape of the ice cream and to prevent it from melting so quickly after it has been removed from a freezer. Perhaps before you visit the ice cream section of your supermarket, you should re-think your purchase.

More worrying is the new Gardasil cervical cancer vaccine which is being injected into girls aged 9-26.

“Gardasil contains Polysorbate 80, which is linked to infertility in mice,” noted Dee Nicholson, National Communications Director for Freedom in Canadian Health Care.

Read more: Polysorbate 80 Causes Infertility: An Emulsifier That Can Damage Your Reproductive Health - http://infertility.suite101.com/article.cfm/polysorbate_80_causes_infertility#ixzz0CDMH6UOp
 

kinabaloo

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It is likely used to emulsify oil soluble favors. The oil may be left in the atomiser depending on its boiling point; the concensus on that being not a good thing. The polysorbate will likely be evaporated best i can tell and inhaled. It's also an irritant. Best to avoid those flavors containing it. I think there is a list somewhere of safe flavors; perhaps someone can check and update it ...
 

AGNES PEACOCK

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Thank you for the information MonkeyMonk, very interesting. As consumers today we have to keep ourselves informed as to what we are putting in our bodies.

Hopefully you dont get flamed as I have by those who prefer to put their heads in the sand. Stating facts and informing others should not be met with yelling or sarcasm.

Thank you again, as I prefer to know, rather than not know. Only then can I make my informed choice as to what I choose to consume.
 

Phalse

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Gardasil cervical cancer vaccine

should be given to all girls at those ages.
This injection will prevent (as in it makes them immune to) the more powerful herpes virus strains that often causes cancer in women!

You can't die or be harmed in anyway from a small chemical dose of Polysorbate.

Now smoking it for prolonged use, probably can lead to some type of damage, like infertility. Just like most chemicals do.
 

Walrus

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Idahojo

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ZambucaLu

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Polysorbate 80 is also already used in pharmaceutical suspensions. It's been approved as safe for inhalation:

Polysorbate 80 as a nonionic surfactant, is widely used in liquid pharmaceutical products such as inhalation suspensions and nasal suspensions.

ScienceDirect - Journal of Chromatography A : High-performance liquid chromatographic determination of polysorbate 80 in pharmaceutical suspensions

Thanks for researching this Walrus. Now...I have never seen a loranns listing this ingredient. Do you know which ones contain it? Just curious....never noticed it before.

Lu
 

MonkeyMonk

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I'm away from home at the moment, but I hope to post a list later. Relative to scientific studies, there will always be ones in apparent conflict. (I cannot see my 1st post from my iPhone but the last link I believe was a scientific journal or study.) I'm glad Walrus posted a different view point and I will be reading his link too when I get home. One is best informed when they see both sides of the coin.
 

Walrus

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Thanks for researching this Walrus. Now...I have never seen a loranns listing this ingredient. Do you know which ones contain it? Just curious....never noticed it before.

Lu
edit... late to the draw, never mind.

Potassium Sorbate is also ok. I posted links on these before, but don't have time to dig the links up right now... I'm on the job.
 
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katink

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How are the estimates as to how much (or little) is needed to possibly cause damage? And what is it's lifespan before disappearing out of the body (or does it build up perhaps like some poisons for instance are known to do?)?
These factors would be an important part of telling if they need to be taken into account for us e-vapers or not, I think?
 

Letzin Hale

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Polysorbate 80 is also already used in pharmaceutical suspensions. It's been approved as safe for inhalation:

Polysorbate 80 as a nonionic surfactant, is widely used in liquid pharmaceutical products such as inhalation suspensions and nasal suspensions.

ScienceDirect - Journal of Chromatography A : High-performance liquid chromatographic determination of polysorbate 80 in pharmaceutical suspensions

Firstly, I am not questioning anyone's integrity and I respect people's opinions more when they have made some effort to research a topic, especially on public forums which have proven themselves good breeding grounds for panic and hysteria. This post is not in any way personal and is intended to be a positive contribution.
I do however have some doubts and find it difficult to accept reassurance that certain chemicals are safe to use in electronic cigarettes without seeing relevant evidence.
I have read the linked article at Science Direct but could only access the 'abstract' version which gives a very brief outline of what the article is about. I could have paid over 30 Dollars to register and have access to the full article but I do not have that kind of money to throw around.
Possibly Walrus has access to it and there is further pertinent information? The article dates from 2002 and is quoted below in red. My comments are below that. The Material Safety Data Sheets indicate a general safety regarding inhalation, but we all know that there is a major, significant difference between their interpretation of inhalation and ours, that being that we inhale substances after they have been heated to a point of vaporisation, something which up until now would not have been considered as normal practice when compiling data sheets.

Received 23 July 2002; revised 7 November 2002;
accepted 8 November 2002. ;
Available online 10 December 2002.

Abstract

A quick HPLC method is reported for the analysis of polysorbate 80 in pharmaceutical suspensions. A typical pharmaceutical suspension was mixed with dilute potassium hydroxide, and heated at 40 °C for 6 h. This procedure resulted in quantitative hydrolysis of polysorbate 80 to release oleic acid. A quick HPLC procedure was used to analyze the hydrolyzed samples without further sample treatment. Polysorbate 80 USP, treated in the same way as the pharmaceutical suspensions, was used as standard. Full validation tests were carried out and the validation studies demonstrated that this method is suitable for accurate and reproducible analysis of polysorbate 80 in pharmaceutical suspensions.


Oleic and monounsaturated fatty acids have been associated with increased risk of breast cancer as indicated in the article linked to below. Again this is an 'old' article but one which should be considered. There are also articles available regarding oleic acid and its relationship to acrolein, a chemical which has a thread of its own on here. Most of us are not qualified in chemistry but we all have the right to ask questions and for those questions to be answered.

Erythrocyte Membrane Fatty Acids and Subsequent Breast Cancer: a Prospective Italian Study

There is no doubt a mass of evidential research that we could and should consider before pronouncing something as safe to use. I do not mean to be alarmist but we are dealing with a strange new form of imbibing chemicals and although most of us believe that it is far safer than smoking (I do because I vape) we should still be encouraging questions, research and debate in order to determine how safe or unsafe vaping is rather than accepting general evidence that doesn't really apply to heated vaporisation.
I remember too well the Thalidomide horror and had a schoolfriend who was born with terrible deformities because of the drug which had been proclaimed safe. Yes, it was a long time ago and we now have greater controls over testing and use of drugs & chemicals and greater awareness, communication and dissemination of information, which is all the more reason for us to insist on product testing and regulation. There, I said it, the 'R' word! If anyone thinks they can convince me that electronic cigarettes, and particularly the liquids sold for use in them, should remain unregulated then please try. Regulation would prevent those who refused to comply with safety standards from actively marketing their products - is that a bad thing? Of course there would be the 'cowboys' and unscrupulous scumbags who would try to sell fake/unsafe goods, but we would be able to tell who they were and would have a more clearly defined choice as to what we were buying.
If, God forbid, any one of us were to suffer ill effects or our offspring were born with some infirmity and it was found to be related to vaping an untested substance that we had been sold on the open market, then there would be the inevitable question "Why were we not told?", followed by the inevitable lawsuits. I would rather see our ecigs tested and declared safe to use both from a personal and philanthropic perspective as it would help them to become a mainstream product and hopefully help to eradicate tobacco smoking.
Alan.







http://www.chestjournal.org/content/106/3/925.full.pdf
 
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Walrus

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Letzin Hale,

If it's not a risk you want to take, then don't. It's as simple as that, really. My point was that Polysorbate 80 is already being used in inhalers, for better or worse... and that the miniscule amount in Root Beer flavorings (especially when you are only using maybe 10% in a mix) is a risk I'm willing to take, even more so when compared to the crap in cigarettes.

Your mileage may vary.
 
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