Early in my DIY journey I was using a couple of ingredients that were making my mixes cloudy. Someone pointed me to one of Bill's Magic Vapor
blogs (on the subject); where he suggests mixing all PG based ingredients first, followed by VG. It worked... no more cloudy mixes. It is just habit now and I still mix that way today. Flavors first, followed by PG, a quick vigorous mix, then add my VG based nic and another quick vigorous mix (my rationale is; that this is as thin as my VG dominant recipe is going to be, so start the nic dilution while it is easiest... though I have NO CLUE whether it does one iota of good!
), and finally the VG followed by a thorough mix. Now it is all just habit, and I doubt it has any serious advantage over any other method. But, I like my results, and that is all that matters to me.