I hate to admit this in a public forum.  I understand very little of what has been written.  My take away has been that lowering the temperature of the vape is generally considered to be "safer" - if "safer" is the correct word to use (my preference has generally been "risk reduction"). 
Endeavoring to do so, I have changed have been changing the coil build for use in my mechanical squonkers.  I aim for a "heat flux" number in what is considered to be the rather cool range.  I use the old style of the Steam Engine coil calculator. 
Now, to the question, has my take away from what I have read been correct?  Does the cooler coil, in some way, mimic the beneficial effect of temperature control in regulated mods?
@mikepetro I have to thank you for the work you have put into this project, it is obviously extensive and time intensive.  I wish that I had the educational background to understand all of it (or, after reading my post, you may wonder if I understood any of it

).