The only juice I've tried in there is Elvis Presley from diyflavorshack. I haven't detected any taste from the vinyl leeching into the juice. My local stores don't carry the Polycarbonate tubes, which was my first choice. But after much Google'ing I could not find anything suggesting that there would be an issue with the vinyl. They do use it in soda machines and distilleries so I assume it would be safe.