I have been vaping for 8 years now and hit a place where I was wanted something different from the way I have been vaping. Hence the lower ohms, more air, etc. First of all I hate labels, but for the purpose of explaining I will try to stay within whatever defines a mtl or dl vaper. It is generally excepted that any ohm 1.0 and above is considered mtl and any coil with ohms lower that 1.0 is dtl. Me, I seem to be all over the place because the flavor is what I am really wanting and sometimes to find it I have to try out all sorts of different set ups.I have no experience with there being a big difference in a recipe...made for/by someone who does MTL vs. DTL, no nic vs. with nic, low wattage vs. high wattage, nor with various gear and builds. Another ECF member and I commonly use nearly the identical % of flavorings in eliquid recipes that we both make. He makes his DIY at 80VG/20PG @ 3mg and I make mine 60VG/40PG @ 7mg. However, he vapes the exact opposite as I do in every way. He vapes only DTL, at very high watts, and with fancy coils he builds at like 0.2ohms and lower. His gear includes things like a Hammer of God beast size mod and mods he builds himself, with the Voltrove (IIRC 20-24mL capacity) and similar others.
I make eliquids for a couple friends and a relative, who also have differences in how they vape, the gear they use, their nic mg, PG/VG ratios, etc., compared to me. They all like the same recipe made for them, flavoring-wise, as I make it for myself...with only the adjustments made for their different nic mg and PG/VG ratios.
It's just a new-to-me idea...that "what works for you would never work for me, and I assume vice versa." Not saying it's not true in your case though. Just something I'd never heard before.
On some of my mixes, I don't have to do anything to the juice, I get good flavor etc on whatever tank/coil set up. One some of my others, the higher I go up in power the flavor starts to disappear and I think the heat has something to do with that. So I am left with a choice of either putting the flavor in a known mtl tank and continue to enjoy until that mix is finished or try adding more flavoring which may or may not work. It makes more sense to wait until I need to mix more to wait to adjust any taste solutions to lower ohms, higher wattage. As I mentioned before, I am finding the cream, dessert types of flavors are more of the ones in question. I do not do many creamy type of mixes but I do love my coconut cheesecake mix but atm can only taste in a coil at .6 ohms @10watts. Any higher wattage and the flavor disappears.
So having said all of that, I think there are always exceptions to the one size fits all theory, even tho it does appear for fruit flavors to be true, at least for my taste buds. I can taste in any ohm coil all of the one stop mixes I get from Kimberely, and all of my standalone 1 or 2 flavor mixes without any adjustments at all.
Just my 2 pennies.