I wouldn't call it a guess.
It is a quite straightforward calculation:
If you solve this equation for resistance change in % you would get this:
(R(T)/R(0) -1)*100=1+α*(T-T(0)= resistance change in %, where α=TCR and it is not initial resistance dependent
bottom line:
you set your target temperature for a given initial resistance and the mod will calculate your target resistance.
And it doesn't matter how big your initial resistance is as long as the target resistance is within the limitation of the mod
However, what does matter is your target temperature.
Ni has a significantly non linear TCR curve and its TCR is increasing by temp, meanwhile Tis TCR is almost constant.
Means, the higher your target temp is the bigger temp offset you need to use a DNA40 with Ti.
With a DNA200 or a device with manual TCR settings is not an issue thought.