propylene glycol, and glycerine...... see this, if you havent already.

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DWTaylor

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see now the thing is we do want to know what is the health risks we are taking. I thank you for finding the information and posting it.
BUT if you are really that worried I might suggest that you look into pills, gum, patch, snuz, or snuff to help quit.
Cause I know that if I were to see someone go to this length to tell others how bad it is and then continue to use said product I know I would lose all respect in them.
So I'll end this post of mine with a thanks for the information, and the time getting that information, and sorry that this great product isn't for you.
 

V4Lis4me

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Excellent--you play dark and digg deep---What we are saying is that this is new to you and you should satisfy yourself and have an open discussion about it until you feel you have come upon the right information that makes you feel comfortable. And if you can not find it with others---then do not use the e-cig--use some other alternative, quit, or go back to analogs. A couple of people tried to chime in and gave their opinions.

If you are looking for anything more then opinions you are not going to find them as extensive and long term testing have not been done to any great degree.


Sun


Very well put indeed. Personally, I hadn't invested much time in the area previous to this. So I was startled to say the least. We all are in fact the "guinea pigs" so to speak. What I do find greatly reassuring is the fact that the overwhelming majority seem to tolerate ecigs just fine.
 

inicapem

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I don't understand why people seem to get so upset on this forum when someone posts about the "potential" long-term health issues of PG and VG. No one knows for sure, so what is wrong with looking at different research, posting it, and discussing it? Why is it so necessary to close our eyes? I am very happy that I found ecigs, but I'm not going to fool myself that there may not be repercussions down the line - it is my choice and I am taking that chance. But that shouldn't rule out my wanting to know more info as studies come out. This shouldn’t be so black & white, i.e. either you’re with us or against us mentality.

As for the asthma inhaler debate, my BF also has asthma and I read the ingredients on his inhaler and did not see PG. Other brands may have it though. But I really find that a moot point. People don't suck on inhalers like we suck on ecigs. They use it when their lungs are constricted which could mean they don't use it for days or even months at a time, which as the OP's article said “CHRONIC EXPOSURE”. Asthma inhaler usage is NOT chronic exposure, nor is eating cookies. However, most people use ecigs chronically.

The OP is not trying to scare anyone, just reporting on research he found and wanting to have a discussion. Are we only supposed to post and discuss pro PG/VG/E-cig articles? That seems like a great disservice to the community. I believe in looking at all sides of a topic, whether I agree with them or not.
 
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kristin

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I don't understand why people seem to get so upset on this forum when someone posts about the "potential" long-term health issues of PG and VG.
Who got "upset?" All I've seen is a discussion on whether or not PG is safe to inhale.

Just because you support that PG is safe to inhale doesn't mean you are "upset." I don't know anyone on ECF who wouldn't like confirmation that they are what we expect - safer than tobacco smoke.

The only time I get a little upset is when people seem to have the expectation that ecigs should be 100% safe. That is an unreasonable expectation, because EVERY drug has possible side effects for someone.

Here are the potential reactions from using Proventil inhalers, which do not list PG as an ingerdient: Inhalation Aerosol include: dysphonia, increased sweating, dry mouth, chest pain, edema, rigors, ataxia, leg cramps, hyperkinesia, eructation, flatulence, tinnitus, diabetes mellitus, anxiety, depression, somnolence, rash. Palpitation and dizziness have also been observed with PROVENTIL HFA Inhalation Aerosol.

If it's ok for that FDA-approved product, why is PG any worse?

Rhinarus Mist, sold OTC for dry nasal passages contains PG: Rhinaris • Your TOTAL nasal hygiene solution!

I can't find ingredient lists for inhalers, but I do know a few members have posted that their personal asthma inhaler listed PG in the ingredients.
 

inicapem

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Who got "upset?" All I've seen is a discussion on whether or not PG is safe to inhale.


If it's ok for that FDA-approved product, why is PG any worse?

First off, I personally don't leave my safety up to the FDA, many drugs have been approved, later to be recalled with deadly consequences. But let's go with your argument that PG is approved by the FDA as GRAS - "generally recognized as safe". What you are forgetting is that it is recognized as safe in certain quantities. We know very little about the long term affects of CHRONIC USAGE. As I stated before, using an asthma inhaler or eating cookies is NOT CHRONIC USAGE.

As for my comment that this topic seems to make people on this board upset, that’s just the feeling I’ve gotten reading through different threads on these issues. Many responses to OPs are “you’re trying to scare us” or “then maybe ecigs aren’t for you”. Perhaps it’s just the threads I’ve read, but there seems to be a lot of with us or against us mentality, with little room for discussion on legitimate long term health concerns.
 

kristin

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The more I Google this, the more it seems that PG is actually believed to be CAUSING asthma in some people. I see a lot of patents for devices to use PG for asthma, but I can't find any that list PG in the inhalers - only the oral medications.

Of course, asthmatic people shouldn't be smoking, either! My sister-in-law smoked and had asthma and she's doing better using the ecigs. Go figure.

But it's hard to believe that we can safetly drink PG or inject PG directly into our viens, but we can't inhale it. That just doesn't make any sense. I do remember reading some report that said PG doesn't build up in the human body, so, logically, it would be absorbed by the lung tissue and then flushed out of the system.

HSDB Search Results - Frameset
 

kristin

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First off, I personally don't leave my safety up to the FDA, many drugs have been approved, later to be recalled with deadly consequences. But let's go with your argument that PG is approved by the FDA as GRAS - "generally recognized as safe". What you are forgetting is that it is recognized as safe in certain quantities. We know very little about the long term affects of CHRONIC USAGE. As I stated before, using an asthma inhaler or eating cookies is NOT CHRONIC USAGE.

As for my comment that this topic seems to make people on this board upset, that’s just the feeling I’ve gotten reading through different threads on these issues. Many responses to OPs are “you’re trying to scare us” or “then maybe ecigs aren’t for you”. Perhaps it’s just the threads I’ve read, but there seems to be a lot of with us or against us mentality, with little room for discussion on legitimate long term health concerns.

The point of my FDA comment was just that - everyone here knows the FDA has approved worse products. That was my point. There is NOTHING 100% safe on the market today, just FDA-approved bad side effects.

Some people do get upset, because if you're here long enough, you'll see trolls condemning ecigs without proof and just scare-mongering. And this topic is found in dozens of old threads.

I think many people get upset for the same reasons I stated - we were SMOKING before. We were exposing ourselves to thousands of toxins and hundreds of carcinogens in high levels. It seems ridiculously demanding to expect ecigs to not only be 4,000 times less toxic than tobacco smoke, but to also be 100% safe. There is no such thing, not even in FDA-approved medications. There will always be side effects of putting anything foriegn in the human body, some people will experience worse rather than better.

Of all the things in ecigs, PG is the least risk. It's used in oral medications, injectable medications and inhaled medications and there are scant few reports of PG poisoning or adverse reactions as a result. It breaks down and is flushed from the human body within 2 days of ingestion. If it were a huge danger, more people would be coming forward with adverse reactions after 5 years on the market.

It just seems so trivial to get up-in-arms over a "known mild irritant" like PG when most of us were inhaling a tar, arsenic, acetone, butane, carbon monoxide, hydrogen cyanide and ammonia cocktail a few months ago.

If people have any long-term health concerns, the answer is logical and simple - they should quit inhaling foriegn substances into their lungs, because nothing is 100% safe to inhale.

Discussing the long-term effects of PG is absurd, unless you're talking about how it compares to smoking tobacco, because most of us would otherwise be smoking. The only place this concern would be "legitimate" is if ecigs were an NRT, which they are not for most people.

If anything is a legitimate concern, it's the flavorings - THOSE are the great unkown. But whatever the risk, it's still a hell of a lot less than smoking tobacco.
 
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5cardstud

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Well also you take extremely more risk driving than flying but I see the freeways are very congested today and there is alot of room in the sky and what about charbroiled hamburgers? There is as much tar in a charbroiled hamburger as there is in a pack of cigs but everybody still has meat bbqing on the grill every summer. Life is dangerous and if it comes to smoking with 1000s of chemicals proved to be bad or vaping with a chemical that is suspect and is also already in the foodchain I'll pick vaping anyday.
P. S. Kristin has it right.
 
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Mister

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http://www.nature.com/nrneph/journal/v3/n9/full/ncpneph0573.html
...
The World Health Organization recommends a maximum dietary propylene glycol intake of 25 mg/kg/day (i.e. 1,875 mg/day for a 75 kg male).17 The patient described here received an average intravenous propylene glycol dose of 212 g/day (2,827 mg/kg/day).

I find this case rather encouraging. Most of us seem to be vaping 2 to 3 ml per day, i.e. 2 to 3 g/day. That's not hugely out of line vs. the WHO maximum recommendation of a bit less than 2g/day for a 75kg person.

The patient in the cited case received roughly 100 times that level of PG over a seven day period (212 g/day.) At 100* as much there are many normally harmless substances which would become harmful. Heck, just think about increasing your daily water intake by *100, I imagine that could well be fatal.

I'm not saying we can know that PG is safe, just saying that this case study is encouraging.
 

PlanetScribbles

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I have consoled myself in the safe assumption that a little PG per day could not possibly be as dangerous as the crap I was inhaling 40+ times per day for the past 25 years.
I simply cannot see a comparison on the dangers of PG/VG vs tobacco. Nothing is 100% safe, there are varying degrees of danger in everything we consume.
 

anim8r

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I've read these many, many times.



factoid: They use propylene glycol in asthma inhalers. People who have sensitive lungs use those inhalers. If it was so bad to inhale, wouldn't there have been massive recalls of those inhalers?









MSDS Sheets are usually worst case scenarios, with excessive exposure or people with certain conditions that make them higher risk. They are CYA for companies - same as those disclaimers on drug commercials. They have to list every known reaction that anyone ever had as a possible risk, even if it wouldn't even affect 99% of the people.



Health Canada cited PG simply as a "known irritant" in it's attempt to scare people. Sure, it's on the MSDS as a possible irritant - to people who have never smoked a pack a day of toxic tobacco. We were sucking in ammonia and arsenic. I highly doubt it'd be an irritant to most former smokers! lol

Exactly.



Now, to the original poster,
post the fact sheets for cigarettes and your original links look like they were testing sugar water.

I agree we need some testing, but in direct correlation to vaping, and not a study of possible risks from working at factories that are subjected to possible spills or accidental injesting of large quantities.
 
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anim8r

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Very well put indeed. Personally, I hadn't invested much time in the area previous to this. So I was startled to say the least. We all are in fact the "guinea pigs" so to speak. What I do find greatly reassuring is the fact that the overwhelming majority seem to tolerate ecigs just fine.

I exercise now (I didn't when I was smoking).
I'm losing weight and feeling fit. I even climb the stairs at work instead of using the elevator.

I lost my chronic cough (of 22 years) within 2 weeks of vaping.
I haven't been sick since I started vaping and stopped smoking.

I no longer stink of smoke.

I'm eating healthier, I feel much much healthier.


In the right amount, water can kill you.

Same with Oxygen.

I also agree there should be tests on prolonged use of eliquids and ecigs. I don't think you'll find anyone that disagrees with that.

And, brother, I can GUARANTEE the FDA is/has been testing. They WANT to ban ecigs. In a really really bad way. I'm sure their pockets are lined by tobacco and we all know they are funded by the government. All three of these groups have made nothing but negative remarks concerning ecigs and yet can't produce a single shred of evidence that even comes remotely close to the facts concerning the effects of cigarettes on the human body.
 

V4Lis4me

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Exactly.



Now, to the original poster,
post the fact sheets for cigarettes and your original links look like they were testing sugar water.

I agree we need some testing, but in direct correlation to vaping, and not a study of possible risks from working at factories that are subjected to possible spills or accidental injesting of large quantities.


Now we ALL know that real cigs are bad, REALLY BAD for our health!
The point is that, from what I have come to realize that..... we simply DO NOT know if ecigs are really bad for our health. This is not supposed to be a comparison of real cigs to ecigs, because I do believe that all of us in here feel that ecigs are the lesser of two evils..... otherwise we would be smoking still.
This is just information that is being conveyed about the products that we ingest on a daily basis, no more.... no less.

 

V4Lis4me

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i exercise now (i didn't when i was smoking).
I'm losing weight and feeling fit. I even climb the stairs at work instead of using the elevator.

I lost my chronic cough (of 22 years) within 2 weeks of vaping.
I haven't been sick since i started vaping and stopped smoking.

I no longer stink of smoke.

I'm eating healthier, i feel much much healthier.


In the right amount, water can kill you.

Same with oxygen.

I also agree there should be tests on prolonged use of eliquids and ecigs. I don't think you'll find anyone that disagrees with that.

and, brother, i can guarantee the fda is/has been testing. They want to ban ecigs. In a really really bad way. I'm sure their pockets are lined by tobacco and we all know they are funded by the government. All three of these groups have made nothing but negative remarks concerning ecigs and yet can't produce a single shred of evidence that even comes remotely close to the facts concerning the effects of cigarettes on the human body.





now that is straight up true!!!!!!!
And i agree 100% with you!!!!
 

anim8r

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now that is straight up true!!!!!!!
And i agree 100% with you!!!!

Thanks

And, it needs to be said. I don't condone the continued or prolonged use of e-cigs. I hope to hell I'm not vaping a year or 2 from now, but I also know I'll take up vaping again LONG before I take up smoking again.
 

USinchains

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We can't start assuming our mg per day intake of PG until the vapor is studied, we don't know what takes place at the point of ignition, how much of the formula remains stable or possibly is broken down. We don't know the absorption rate of PG (in vapor) for the average vaper. Unless I'm missing some important threads in here that have all this info, we'll just speculate until the act of vaping is studied, deeply, the vapor as well as the body of the user. That said, posting all this cryptic MSDS info and sources for side effects etc and raising concerns may actually lead to these tests being done, someday.
 

VallyGrlOR

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I was wondering if any diabetics have had problems with their blood sugar levels with using either PG or VG. The info I have found is that both are converted into glucose in the body. I am a type 2 diabetic and I am not on medication, trying to control it naturally (one of the reasons I want to stop smoking analogs! ) anyway I searched for about an hour now and can't find anyone discussing this, so was wondering if there are any other diabetics vaping? I saw one lady say she was a type 1?
 

voltaire

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I was wondering if any diabetics have had problems with their blood sugar levels with using either PG or VG. The info I have found is that both are converted into glucose in the body. I am a type 2 diabetic and I am not on medication, trying to control it naturally (one of the reasons I want to stop smoking analogs! ) anyway I searched for about an hour now and can't find anyone discussing this, so was wondering if there are any other diabetics vaping? I saw one lady say she was a type 1?

A bit OT, but here's two links for you:
http://www.e-cigarette-forum.com/fo...else-notice-decrease-appetite.html#post964574

http://www.e-cigarette-forum.com/forum/health-safety-e-smoking/1670-diabetes-vg-use.html#post28714
 
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