This is the key hedge against small businesses by the FDA:
“Most vape businesses like ProVape don’t have the means or wherewithal to put our products through this cost-prohibitive process and
with no guarantee it would get approved.”
How many can even take that chance if they even could come up with the money??? It would be better off, if they had to pay that money to the FDA - at least, then the FDA would have a profit incentive

... but "profit" is a dirty word to them and their ilk.
How many times have you heard a politician or some "public servant" when they were getting grief from the citizens, something like: "I could be doing well in the private sector but I've decided to dedicate myself to public service"
Here's the reality - The private entrepreneur doesn't have (or shouldn't have) tax money to prop up their business and as is usual in gov't, a big debt - whether it is a the local school level to the Federal level where they are borrowing funds to continue their departments existence.
IF the "public servant" would run a business like they run their department (whatever it is), they'd be bankrupt in a month. So don't fall for this common 'plea' from your public servants or politicians - they have a way too big estimation of their ability and many of them are failed business people. Either that or they went directly from 4 to 8 years of college to a gov't job without any experience in business at all.