I use mostly tobacco flavors and routinely just refill with the "flavor de jour". It only takes a few hits, then the new flavor is there. Sometimes the mix is really good, which makes me wish I could figure out the ratios of flavors, and sometime just blah. Worst case, a rinse, dry with a paper towel or tissue, refill and go. Rayon does not actually absorb like cotton does. It transports the liquid instead so that makes it pretty easy to change flavors. I've used builds to the point of not being able to see the coil for all the gunk, rinsed it, and the rayon comes back pristine white. YMMV as with everything vape related.